Confusion and Alarm About A Drug in Use for 60 Years: Hydroxychoroquine

With all the alarming talk about the President taking hydroxychloroquine, I decided to look into the side effects. If my husband or I was exposed to covid-19, would we consider taking it?

I did an internet search and the first site to pop up was drugs.com

When I looked at the list of side effects I was astonished. I had never seen such a long list for a medication. I counted 52 side effects. It was noted that the incidence of these side effects was unknown.

Because this medication has been around for a long time I decided to look in the 2003 Nurses Drug Guide that I have on my book shelf.

This reference listed 20 side effects that occur 1% of the time or more. It listed 2 rare side effects. Hydroxychloroquine was approved for use in the United States in 1955.

Hydroxychloroquine is given as a preventive medicine (prophylaxis) in places where malaria is common. It is also used to treat malaria. It works by inhibiting the replication of the parasite in the body. It is thought, that in the same way, this medication may inhibit the replication of the corona virus in the body. 

A second use for hydroxychloroquine is in the treatment for rheumatoid arthritis or lupus. This treatment is longterm. This drug guide instructs: Learn about adverse effects and their symptoms when taking prolonged therapy.

As a nurse I realize that dosage, timing and duration of use of a medication are important considerations. If hydroxychoroquine is used as a preventive medication after exposure to cover-19 it is important to study dosage for a short term use.

Today (6/2/2020) an article in the Wall Street Journal echoes the questions and concerns that I have about the confusing messages regarding the use of this medication, which has been safely used for over 60 years. The article by Allysia Finley titled “The Lancet’s Politicized Science on Antimalarial Drugs” includes this observation.

In an open letter to the Lancet’s editors and the study’s authors, some 120 doctors, statisticians and epidemiologists write that the headlines about the study “have caused considerable concern to participants and patients enrolled in randomized controlled trials”evaluating the drugs. Thus many researchers have scrutinized the data, and the “scrutiny has raised both methodological and data integrity concerns.”

In light of the great number of vaccines given to children that have not gone through adequate safety studies and the known vaccine injuries, I find the exaggerated concern over hydroxychoroquine to be mind boggling.

Doctors need a good study that looks at dosage of hydroxychloroquine and the correct timing for prescribing it. Is it a good prophylactic?

Photo credit: Brett Jordan on Unsplash

The Pandemic Challenges Our Faith

Recently I read Tessa Afshar’s book, Daughter of Rome. The book is historical fiction centered on Priscilla of the Bible. One of the events told in the book is the couple’s forced move out of Rome. The Bible states that this happened.

After this Paul left Athens and went to Corinth. And he found a Jew named Aquila, a native of Pontus, recently come from Italy with his wife Priscilla, because Claudius had commanded all  Jews to leave Rome. And he went to see them, and because he was of the same trade he stayed with them and worked, for they were tentmakers by trade. Acts 18:1-3

Priscilla and Aquila experienced a sudden change in their life. They had to establish their tent making business in a new locale and adapt. The unexpected blessing was meeting Paul in Corinth.

Afshar’s book is rich in color—she knows the Middle East. The Bible provides limited information about Priscilla, so many of the events in her book are imagined, but could have happened. I especially appreciate the themes of faith and forgiveness woven through the book.

With the worldwide pandemic we have experienced a sudden change in our lives. I don’t think I feel the crunch as much as some. I have adequate food. I am already retired from nursing (although I dreamed that I was going back to work). I am able to stay in touch with friends and family over social media and zoom.

My prayer is that I will be alert to ways that I can help. I have the time available to pray for our country, for people with illness or economic uncertainty, and for countries that are devastated by the corona virus.

The pandemic brings the realization that we are not as much in control as we think we are. God is sovereign and offers his love and guidance. Through Jesus we can have a relationship with God. If you have not repented and asked Jesus to be your Savior I encourage you to do this.

This post is shared with the Five Minute Friday writing community.

A Time for Steadfast Faith

Currently I am studying the book of Ezra with women of my church. We looked at the reason that God allowed Israel’s captivity in Babylon. One reason was their failure to give the land its Sabbath rest. I read about the Sabbath rest that God commanded his people. I have been chewing on this. What would it look like today?

The Lord spoke to Moses on Mount Sinai, saying, “Speak to the people of Israel and say to them, When you come into the land that I give you, the land shall keep a Sabbath rest to the Lord. For six years you shall sow your field, and for six years you shall prune your vineyard and gather its fruits, but in the seventh year there shall be a Sabbath of solemn rest for the land, a Sabbath to the Lord. You shall not sow your field or prune your vineyard . . . . The Sabbath of the land shall provide food for you . . . Leviticus 25: 1-4, 6

God commanded an amazing pause in their activity. Was it for more time in relationship to Him and their family?

The pandemic is leading to cancellations in events, conferences and sports. It is a time to pause.

Less time for busyness and distraction.

More time for family meals. More time for Bible study and reflection. More time to be aware of the needs of our neighbor. More time to pray for nurses, doctors and health care providers. More time to pray for revival.

A time for steadfast faith.

UPDATE 3/17/2020: For families with children home from school it can be a challenge to find materials to keep children busy. My daughter is using Louie Giglio’s book, How Great is Our God: 100 Indescribable Devotions About God and Science, for devotions and to launch some study of science.

This also is a good time for children to help with household activities–cooking, baking, cleaning and laundry.

This post is shared with Kate’s Five Minute Friday writing community. Today’s prompt is: LESS I am also joining the link-up with Anita’s Inspire Me Monday.